Anthocyanin-rich mulberry fruit improves insulin resistance and protects hepatocytes against oxidative stress during hyperglycemia by regulating AMPK/ACC/mTOR pathway
This study evaluated the capacity of mulberry anthocyanin extract (MAE) on oxidative damage alleviation and related protein expression regulation in HepG2 cells and type 2 diabetic mice. In vitro, exposure of cells to high glucose and palmitic acid resulted in ROS and O2− accumulation, mitochondria...
Main Authors: | Fujie Yan, Xiaodong Zheng |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-03-01
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Series: | Journal of Functional Foods |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464617300373 |
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