Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene

Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene

Zinc(II) halides and perchlorate react with 1,4-bis(benzimidazol-2-yl)benzene (L) in 1 : 2 molar ratio in n-butanol/2-methoxy ethanol (10 mL) at refluxing temperature to produce white/pale yellow-colored complexes of the formulae [ZnCl2L]H2O, [ZnBr2L]3H2O, and [Zn(OClO3)2L]HOCH2CH2CH2CH3. Zinc(II) i...

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Main Author: G. Krishnamurthy
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2013/265107
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spelling doaj-c8bed9c9da8c4e1498c7bd4572ebc1e12020-11-24T22:38:44ZengHindawi LimitedJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/265107265107Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzeneG. Krishnamurthy0Department of Chemistry, Sahyadri Science College (Autonomous), Kuvempu University, Shimoga-577203, Karnataka, IndiaZinc(II) halides and perchlorate react with 1,4-bis(benzimidazol-2-yl)benzene (L) in 1 : 2 molar ratio in n-butanol/2-methoxy ethanol (10 mL) at refluxing temperature to produce white/pale yellow-colored complexes of the formulae [ZnCl2L]H2O, [ZnBr2L]3H2O, and [Zn(OClO3)2L]HOCH2CH2CH2CH3. Zinc(II) iodide also reacts with L in 1 : 2 molar ratio in n-butanol (HOCH2CH2CH2CH3) to yield white-colored complex of the formula [ZnL2(OCH2CH2CH2CH3)2]. The complexes were characterized by elemental analysis, molar conductance measurements, thermal analysis, and IR, 1H-, 13C-NMR spectral studies. The complexes showed significant anthelmintic activity. The minimum energy configuration has been obtained for the zinc complexes using molecular modeling Pro Plus; a tool developed by ChemSW, inc, USA.http://dx.doi.org/10.1155/2013/265107
collection DOAJ
language English
format Article
sources DOAJ
author G. Krishnamurthy
spellingShingle G. Krishnamurthy
Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene
Journal of Chemistry
author_facet G. Krishnamurthy
author_sort G. Krishnamurthy
title Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene
title_short Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene
title_full Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene
title_fullStr Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene
title_full_unstemmed Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene
title_sort synthesis, molecular modeling, and biological activity of zinc(ii) salts with 1,4-bis(benzimidazol-2-yl)benzene
publisher Hindawi Limited
series Journal of Chemistry
issn 2090-9063
2090-9071
publishDate 2013-01-01
description Zinc(II) halides and perchlorate react with 1,4-bis(benzimidazol-2-yl)benzene (L) in 1 : 2 molar ratio in n-butanol/2-methoxy ethanol (10 mL) at refluxing temperature to produce white/pale yellow-colored complexes of the formulae [ZnCl2L]H2O, [ZnBr2L]3H2O, and [Zn(OClO3)2L]HOCH2CH2CH2CH3. Zinc(II) iodide also reacts with L in 1 : 2 molar ratio in n-butanol (HOCH2CH2CH2CH3) to yield white-colored complex of the formula [ZnL2(OCH2CH2CH2CH3)2]. The complexes were characterized by elemental analysis, molar conductance measurements, thermal analysis, and IR, 1H-, 13C-NMR spectral studies. The complexes showed significant anthelmintic activity. The minimum energy configuration has been obtained for the zinc complexes using molecular modeling Pro Plus; a tool developed by ChemSW, inc, USA.
url http://dx.doi.org/10.1155/2013/265107
work_keys_str_mv AT gkrishnamurthy synthesismolecularmodelingandbiologicalactivityofzinciisaltswith14bisbenzimidazol2ylbenzene
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