Action and traction: cytoskeletal control of receptor triggering at the immunological synapse

It is well known that F-actin dynamics drive micron-scale cell shape changes required for migration and immunological synapse formation. In addition, recent evidence points to a more intimate role for the actin cytoskeleton in promoting T cell activation. Mechanotransduction, the conversion of mech...

Full description

Bibliographic Details
Main Authors: Janis K. Burkhardt, William A Comrie
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00068/full