Synthesis of indole-based propellane derivatives via Weiss–Cook condensation, Fischer indole cyclization, and ring-closing metathesis as key steps

A variety of highly functionalized indole-based [n.3.3]propellane derivatives is described. The synthesis of the propellane derivatives involves a Weiss–Cook condensation, a Fischer indole cyclization, and a ring-closing metathesis as key steps.

Bibliographic Details
Main Authors: Sambasivarao Kotha, Ajay Kumar Chinnam, Arti Tiwari
Format: Article
Language:English
Published: Beilstein-Institut 2013-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.9.307
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spelling doaj-c88e1f2905644dfe8a359b5855d677e82021-02-02T01:38:29ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972013-11-01912709271410.3762/bjoc.9.3071860-5397-9-307Synthesis of indole-based propellane derivatives via Weiss–Cook condensation, Fischer indole cyclization, and ring-closing metathesis as key stepsSambasivarao Kotha0Ajay Kumar Chinnam1Arti Tiwari2Department of Chemistry, Indian Institute of Technology-Bombay, Powai, India, Fax: 022-2572 7152Department of Chemistry, Indian Institute of Technology-Bombay, Powai, India, Fax: 022-2572 7152Department of Chemistry, Indian Institute of Technology-Bombay, Powai, India, Fax: 022-2572 7152A variety of highly functionalized indole-based [n.3.3]propellane derivatives is described. The synthesis of the propellane derivatives involves a Weiss–Cook condensation, a Fischer indole cyclization, and a ring-closing metathesis as key steps.https://doi.org/10.3762/bjoc.9.307allylationindole derivativespropellanesring-closing metathesisWeiss–Cook condensation
collection DOAJ
language English
format Article
sources DOAJ
author Sambasivarao Kotha
Ajay Kumar Chinnam
Arti Tiwari
spellingShingle Sambasivarao Kotha
Ajay Kumar Chinnam
Arti Tiwari
Synthesis of indole-based propellane derivatives via Weiss–Cook condensation, Fischer indole cyclization, and ring-closing metathesis as key steps
Beilstein Journal of Organic Chemistry
allylation
indole derivatives
propellanes
ring-closing metathesis
Weiss–Cook condensation
author_facet Sambasivarao Kotha
Ajay Kumar Chinnam
Arti Tiwari
author_sort Sambasivarao Kotha
title Synthesis of indole-based propellane derivatives via Weiss–Cook condensation, Fischer indole cyclization, and ring-closing metathesis as key steps
title_short Synthesis of indole-based propellane derivatives via Weiss–Cook condensation, Fischer indole cyclization, and ring-closing metathesis as key steps
title_full Synthesis of indole-based propellane derivatives via Weiss–Cook condensation, Fischer indole cyclization, and ring-closing metathesis as key steps
title_fullStr Synthesis of indole-based propellane derivatives via Weiss–Cook condensation, Fischer indole cyclization, and ring-closing metathesis as key steps
title_full_unstemmed Synthesis of indole-based propellane derivatives via Weiss–Cook condensation, Fischer indole cyclization, and ring-closing metathesis as key steps
title_sort synthesis of indole-based propellane derivatives via weiss–cook condensation, fischer indole cyclization, and ring-closing metathesis as key steps
publisher Beilstein-Institut
series Beilstein Journal of Organic Chemistry
issn 1860-5397
publishDate 2013-11-01
description A variety of highly functionalized indole-based [n.3.3]propellane derivatives is described. The synthesis of the propellane derivatives involves a Weiss–Cook condensation, a Fischer indole cyclization, and a ring-closing metathesis as key steps.
topic allylation
indole derivatives
propellanes
ring-closing metathesis
Weiss–Cook condensation
url https://doi.org/10.3762/bjoc.9.307
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AT ajaykumarchinnam synthesisofindolebasedpropellanederivativesviaweisscookcondensationfischerindolecyclizationandringclosingmetathesisaskeysteps
AT artitiwari synthesisofindolebasedpropellanederivativesviaweisscookcondensationfischerindolecyclizationandringclosingmetathesisaskeysteps
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