Trkb signaling in pericytes is required for cardiac microvessel stabilization.

Trkb signaling in pericytes is required for cardiac microvessel stabilization.

Pericyte and vascular smooth muscle cell (SMC) recruitment to the developing vasculature is an important step in blood vessel maturation. Brain-derived neurotrophic factor (BDNF), expressed by endothelial cells, activates the receptor tyrosine kinase TrkB to stabilize the cardiac microvasculature in...

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Bibliographic Details
Main Authors: Agustin Anastasia, Katrin Deinhardt, Shiyang Wang, Laura Martin, Donna Nichol, Krithi Irmady, Jasmine Trinh, Luis Parada, Shahin Rafii, Barbara L Hempstead, Pouneh Kermani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3909185?pdf=render

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