Immunologic response to vaccine challenge in pregnant PTPN22 R620W carriers and non-carriers.
Influenza infection is a significant cause of respiratory morbidity among pregnant women. Seasonal influenza vaccination engages innate immune receptors to promote protective immunity. A coding polymorphism (R620W) in PTPN22 imparts elevated risk for human infection and autoimmune disease, predispos...
Main Authors: | Shelly H Tien, Juliet N Crabtree, Heather L Gray, Erik J Peterson |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5517002?pdf=render |
Similar Items
-
The PTPN22 C1858T (R620W) functional polymorphism in inflammatory bowel disease
by: Younes Zaid, et al.
Published: (2018-11-01) -
The association of PTPN22 R620W polymorphism is stronger with late-onset AChR-myasthenia gravis in Turkey.
by: Gizem A Kaya, et al.
Published: (2014-01-01) -
The PTPN22 locus and rheumatoid arthritis: no evidence for an effect on risk independent of Arg620Trp.
by: Wan R Wan Taib, et al.
Published: (2010-10-01) -
Studies of the protein tyrosine phosphatase PTPN22/Lyp in Ptpn22 deficient mice
by: Sanchez-Blanco, Cristina
Published: (2015) -
Computational Molecular Phenotypic Analysis of PTPN22 (W620R), IL6R (D358A), and TYK2 (P1104A) Gene Mutations of Rheumatoid Arthritis
by: Noor Ahmad Shaik, et al.
Published: (2019-03-01)