Adaptive Signature Design- review of the biomarker guided adaptive phase –III controlled design

Genomics having a profound impact on oncology drug development necessitates the use of genomic signatures for therapeutic strategy and emerging medicine proposals. Since its advent in the arena of clinical trials biomarker-related predictive methods for the identification and selection of patient su...

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Bibliographic Details
Main Authors: Arinjita Bhattacharyya, Shesh N. Rai
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Contemporary Clinical Trials Communications
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865418301881