How Parkinsonian Toxins Dysregulate the Autophagy Machinery

How Parkinsonian Toxins Dysregulate the Autophagy Machinery

Since their discovery, Parkinsonian toxins (6-hydroxydopamine, MPP+, paraquat, and rotenone) have been widely employed as in vivo and in vitro chemical models of Parkinson’s disease (PD). Alterations in mitochondrial homeostasis, protein quality control pathways, and more recently, autophagy/mitopha...

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Bibliographic Details
Main Authors: Ruben K. Dagda, Elzbieta Janda, Tania Das Banerjee
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:International Journal of Molecular Sciences
Subjects:
MPTP
6-hydroxydopamine
rotenone
paraquat
methamphetamine
autophagy
mitophagy
Parkinson’s disease
Online Access:http://www.mdpi.com/1422-0067/14/11/22163

Internet

http://www.mdpi.com/1422-0067/14/11/22163

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