Opposing and Operated Side Electroacupuncture Generates Similar Analgesic Effects on Pain after Knee Surgery

The purpose of this study was to investigate whether opposing electroacupuncture (EA) could produce similar analgesic effects as operated side EA after knee surgery in rats. Sprague Dawley rats were randomly divided into the sham surgery group, and three surgery groups: opposing EA, operated side EA...

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Main Authors: Hai Huang, Xiuling Song, Jiayou Wang, Man Xing, Bingxin Kang, Chenghao Ma, Wenbiao Li, Wenjun Han, Lianbo Xiao, Yuelai Chen
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2021/6616886
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spelling doaj-c871d235962342bdb58b0e863386e01b2021-05-03T00:01:24ZengHindawi LimitedEvidence-Based Complementary and Alternative Medicine1741-42882021-01-01202110.1155/2021/6616886Opposing and Operated Side Electroacupuncture Generates Similar Analgesic Effects on Pain after Knee SurgeryHai Huang0Xiuling Song1Jiayou Wang2Man Xing3Bingxin Kang4Chenghao Ma5Wenbiao Li6Wenjun Han7Lianbo Xiao8Yuelai Chen9Shenzhen HospitalShanghai University of Traditional Chinese MedicineShanghai University of Traditional Chinese MedicineShanghai University of Traditional Chinese MedicineGuanghua HospitalGuanghua HospitalShanghai University of Traditional Chinese MedicineShanghai University of Traditional Chinese MedicineGuanghua HospitalShanghai University of Traditional Chinese MedicineThe purpose of this study was to investigate whether opposing electroacupuncture (EA) could produce similar analgesic effects as operated side EA after knee surgery in rats. Sprague Dawley rats were randomly divided into the sham surgery group, and three surgery groups: opposing EA, operated side EA, and model. After surgery, compared with the sham surgery group, three kinds of pain behavior test methods (mechanical withdrawal threshold (MWT), cumulative pain score [CPS], and mechanical hypersensitivity of knee) were used to assess the pain behavior of the rats in the surgery groups. After knee surgery, the three surgery groups were intervened for three consecutive days: EA on the nonoperated side in the opposing EA group, EA on the operated side in the operated side EA group, and no intervention in the model group. It was shown that MWT was higher and CPS was lower in the two EA groups than in the model group on the first and second days after surgery. On the third day after surgery, MWT in the two EA groups was the highest among the 3 days, CPS was the lowest among the 3 days, and the number of nonvocalizations in rats also increased compared with the model group. Moreover, the MWT of the nonoperated side increased more in the opposing EA group than in the model and operated side EA groups. This indicated that both opposing EA and operated side EA methods can be used to relieve pain after knee joint surgery.http://dx.doi.org/10.1155/2021/6616886
collection DOAJ
language English
format Article
sources DOAJ
author Hai Huang
Xiuling Song
Jiayou Wang
Man Xing
Bingxin Kang
Chenghao Ma
Wenbiao Li
Wenjun Han
Lianbo Xiao
Yuelai Chen
spellingShingle Hai Huang
Xiuling Song
Jiayou Wang
Man Xing
Bingxin Kang
Chenghao Ma
Wenbiao Li
Wenjun Han
Lianbo Xiao
Yuelai Chen
Opposing and Operated Side Electroacupuncture Generates Similar Analgesic Effects on Pain after Knee Surgery
Evidence-Based Complementary and Alternative Medicine
author_facet Hai Huang
Xiuling Song
Jiayou Wang
Man Xing
Bingxin Kang
Chenghao Ma
Wenbiao Li
Wenjun Han
Lianbo Xiao
Yuelai Chen
author_sort Hai Huang
title Opposing and Operated Side Electroacupuncture Generates Similar Analgesic Effects on Pain after Knee Surgery
title_short Opposing and Operated Side Electroacupuncture Generates Similar Analgesic Effects on Pain after Knee Surgery
title_full Opposing and Operated Side Electroacupuncture Generates Similar Analgesic Effects on Pain after Knee Surgery
title_fullStr Opposing and Operated Side Electroacupuncture Generates Similar Analgesic Effects on Pain after Knee Surgery
title_full_unstemmed Opposing and Operated Side Electroacupuncture Generates Similar Analgesic Effects on Pain after Knee Surgery
title_sort opposing and operated side electroacupuncture generates similar analgesic effects on pain after knee surgery
publisher Hindawi Limited
series Evidence-Based Complementary and Alternative Medicine
issn 1741-4288
publishDate 2021-01-01
description The purpose of this study was to investigate whether opposing electroacupuncture (EA) could produce similar analgesic effects as operated side EA after knee surgery in rats. Sprague Dawley rats were randomly divided into the sham surgery group, and three surgery groups: opposing EA, operated side EA, and model. After surgery, compared with the sham surgery group, three kinds of pain behavior test methods (mechanical withdrawal threshold (MWT), cumulative pain score [CPS], and mechanical hypersensitivity of knee) were used to assess the pain behavior of the rats in the surgery groups. After knee surgery, the three surgery groups were intervened for three consecutive days: EA on the nonoperated side in the opposing EA group, EA on the operated side in the operated side EA group, and no intervention in the model group. It was shown that MWT was higher and CPS was lower in the two EA groups than in the model group on the first and second days after surgery. On the third day after surgery, MWT in the two EA groups was the highest among the 3 days, CPS was the lowest among the 3 days, and the number of nonvocalizations in rats also increased compared with the model group. Moreover, the MWT of the nonoperated side increased more in the opposing EA group than in the model and operated side EA groups. This indicated that both opposing EA and operated side EA methods can be used to relieve pain after knee joint surgery.
url http://dx.doi.org/10.1155/2021/6616886
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