Reduced mRNA and Protein Expression Levels of Tet Methylcytosine Dioxygenase 3 in Endothelial Progenitor Cells of Patients of Type 2 Diabetes With Peripheral Artery Disease

Reduced mRNA and Protein Expression Levels of Tet Methylcytosine Dioxygenase 3 in Endothelial Progenitor Cells of Patients of Type 2 Diabetes With Peripheral Artery Disease

Endothelial progenitor cells (EPCs) with immunological properties repair microvasculature to prevent the complications in patients with diabetes. Epigenetic changes such as DNA methylation alter the functions of cells. Tet methylcytosine dioxygenases (TETs) are enzymes responsible for the demethylat...

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Bibliographic Details
Main Authors: Shi Zhao, Ting Jia, Yang Tang, Xiaotong Zhang, Hong Mao, Xiaojia Tian, Rui Li, Lu Ma, Guoxun Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
endothelial progenitor cells
tet methylcytosine dioxygenases
diabetes with peripheral artery disease
demethylation
diabetes
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02859/full

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