The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo.

The Depsipeptide Romidepsin Reverses HIV-1 Latency In Vivo.

<h4>Unlabelled</h4>Pharmacologically-induced activation of replication competent proviruses from latency in the presence of antiretroviral treatment (ART) has been proposed as a step towards curing HIV-1 infection. However, until now, approaches to reverse HIV-1 latency in humans have yi...

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Main Authors: Ole S Søgaard, Mette E Graversen, Steffen Leth, Rikke Olesen, Christel R Brinkmann, Sara K Nissen, Anne Sofie Kjaer, Mariane H Schleimann, Paul W Denton, William J Hey-Cunningham, Kersten K Koelsch, Giuseppe Pantaleo, Kim Krogsgaard, Maja Sommerfelt, Remi Fromentin, Nicolas Chomont, Thomas A Rasmussen, Lars Østergaard, Martin Tolstrup
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005142

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