Platelet-Stored Angiogenesis Factors: Clinical Monitoring Is Prone to Artifacts

Platelet-Stored Angiogenesis Factors: Clinical Monitoring Is Prone to Artifacts

Background: The analysis of angiogenesis factors in the blood of tumor patients has given diverse results on their prognostic or predictive value. Since mediators of angiogenesis are stored in platelets, their measurement in plasma is sensitive to inadvertent platelet activation during blood process...

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Main Authors: Patrick Starlinger, Lejla Alidzanovic, Dominic Schauer, Philipp Brugger, Silvia Sommerfeldt, Irene Kuehrer, Sebastian F. Schoppmann, Michael Gnant, Christine Brostjan
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2011-0798
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spelling doaj-c84acaf3814e42bdb5aebb2db24305042020-11-25T00:11:05ZengHindawi LimitedDisease Markers0278-02401875-86302011-01-01312556510.3233/DMA-2011-0798Platelet-Stored Angiogenesis Factors: Clinical Monitoring Is Prone to ArtifactsPatrick Starlinger0Lejla Alidzanovic1Dominic Schauer2Philipp Brugger3Silvia Sommerfeldt4Irene Kuehrer5Sebastian F. Schoppmann6Michael Gnant7Christine Brostjan8Department of Surgery, General Hospital, Medical University of Vienna, Vienna, AustriaDepartment of Surgery, General Hospital, Medical University of Vienna, Vienna, AustriaDepartment of Surgery, General Hospital, Medical University of Vienna, Vienna, AustriaDepartment of Surgery, General Hospital, Medical University of Vienna, Vienna, AustriaDepartment of Surgery, General Hospital, Medical University of Vienna, Vienna, AustriaDepartment of Surgery, General Hospital, Medical University of Vienna, Vienna, AustriaDepartment of Surgery, General Hospital, Medical University of Vienna, Vienna, AustriaDepartment of Surgery, General Hospital, Medical University of Vienna, Vienna, AustriaDepartment of Surgery, General Hospital, Medical University of Vienna, Vienna, AustriaBackground: The analysis of angiogenesis factors in the blood of tumor patients has given diverse results on their prognostic or predictive value. Since mediators of angiogenesis are stored in platelets, their measurement in plasma is sensitive to inadvertent platelet activation during blood processing.http://dx.doi.org/10.3233/DMA-2011-0798
collection DOAJ
language English
format Article
sources DOAJ
author Patrick Starlinger
Lejla Alidzanovic
Dominic Schauer
Philipp Brugger
Silvia Sommerfeldt
Irene Kuehrer
Sebastian F. Schoppmann
Michael Gnant
Christine Brostjan
spellingShingle Patrick Starlinger
Lejla Alidzanovic
Dominic Schauer
Philipp Brugger
Silvia Sommerfeldt
Irene Kuehrer
Sebastian F. Schoppmann
Michael Gnant
Christine Brostjan
Platelet-Stored Angiogenesis Factors: Clinical Monitoring Is Prone to Artifacts
Disease Markers
author_facet Patrick Starlinger
Lejla Alidzanovic
Dominic Schauer
Philipp Brugger
Silvia Sommerfeldt
Irene Kuehrer
Sebastian F. Schoppmann
Michael Gnant
Christine Brostjan
author_sort Patrick Starlinger
title Platelet-Stored Angiogenesis Factors: Clinical Monitoring Is Prone to Artifacts
title_short Platelet-Stored Angiogenesis Factors: Clinical Monitoring Is Prone to Artifacts
title_full Platelet-Stored Angiogenesis Factors: Clinical Monitoring Is Prone to Artifacts
title_fullStr Platelet-Stored Angiogenesis Factors: Clinical Monitoring Is Prone to Artifacts
title_full_unstemmed Platelet-Stored Angiogenesis Factors: Clinical Monitoring Is Prone to Artifacts
title_sort platelet-stored angiogenesis factors: clinical monitoring is prone to artifacts
publisher Hindawi Limited
series Disease Markers
issn 0278-0240
1875-8630
publishDate 2011-01-01
description Background: The analysis of angiogenesis factors in the blood of tumor patients has given diverse results on their prognostic or predictive value. Since mediators of angiogenesis are stored in platelets, their measurement in plasma is sensitive to inadvertent platelet activation during blood processing.
url http://dx.doi.org/10.3233/DMA-2011-0798
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AT lejlaalidzanovic plateletstoredangiogenesisfactorsclinicalmonitoringispronetoartifacts
AT dominicschauer plateletstoredangiogenesisfactorsclinicalmonitoringispronetoartifacts
AT philippbrugger plateletstoredangiogenesisfactorsclinicalmonitoringispronetoartifacts
AT silviasommerfeldt plateletstoredangiogenesisfactorsclinicalmonitoringispronetoartifacts
AT irenekuehrer plateletstoredangiogenesisfactorsclinicalmonitoringispronetoartifacts
AT sebastianfschoppmann plateletstoredangiogenesisfactorsclinicalmonitoringispronetoartifacts
AT michaelgnant plateletstoredangiogenesisfactorsclinicalmonitoringispronetoartifacts
AT christinebrostjan plateletstoredangiogenesisfactorsclinicalmonitoringispronetoartifacts
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