Transcutaneous Auricular Vagus Nerve Stimulation at 20 Hz Improves Depression-Like Behaviors and Down-Regulates the Hyperactivity of HPA Axis in Chronic Unpredictable Mild Stress Model Rats

Transcutaneous Auricular Vagus Nerve Stimulation at 20 Hz Improves Depression-Like Behaviors and Down-Regulates the Hyperactivity of HPA Axis in Chronic Unpredictable Mild Stress Model Rats

Transcutaneous auricular vagus nerve stimulation (taVNS) has gained growing interest as a non-invasive and non-pharmacologic treatment option in various neurological and psychiatric disorders. Animal experiments and clinical trials confirm that taVNS at the auricular concha region has beneficial eff...

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Bibliographic Details
Main Authors: Shaoyuan Li, Yu Wang, Guojian Gao, Xiao Guo, Yue Zhang, Zixuan Zhang, Yifei Wang, Jinling Zhang, Junying Wang, Liang Li, Yongsheng Yang, Peijing Rong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Neuroscience
Subjects:
transcutaneous auricular vagus nerve stimulation (taVNS)
frequency
depressive-like behavior
hypothalamic-pituitary-adrenal (HPA) axis
chronic unpredictable mild stress (CUMS)
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00680/full

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