Synthesis of a 2ꞌꞌ-Deoxy-β-GalCer

Synthesis of a 2ꞌꞌ-Deoxy-β-GalCer

Structural studies of ternary complexes of CD1d/glycosyl ceramides/iNKT cells and CD1d/sulfatide/sulfatide reactive Type II NKT cells have shown how the polar moieties on the glycolipids interact with both the antigen presenting protein (CD1d) and the T cell receptors. However, these structures alon...

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Bibliographic Details
Main Authors: Meena S. Thakur, Archana Khurana, Mitchell Kronenberg, Amy R. Howell
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Molecules
Subjects:
β-GalCer
antigens
NKT cells
CD1d
Online Access:http://www.mdpi.com/1420-3049/19/7/10090

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