| Summary: | Objective: To evaluate the differential diagnostic value of narrow-band imaging (NBI) endoscopy and indigo carmine staining endoscopy in the diagnosis of colorectal hyper-plastic lesions. Methods: A total of 71 lesions form 57 patients were examined with conventional colonoscopy, NBI endoscopy and indigo carmine staining endoscopy to compare and analyze the lesions outlines, pit patterns (PIT) and capillary patterns (CP), so as to distinguish neo-plastic and nonneo- plastic lesions and to compare with the results of pathological diagnosis. Results: The detection rate of conventional endoscopy was 91.5% (65/71), while it was 100% (71/71) under NBI and indigo carmine staining endoscopies, respectively. For the observation of lesion outlines and CP, NBI endoscopy was significantly better than conventional and indigo carmine staining endoscopies, while for the observation of PIT, NBI endoscopy was evidently better than conventional one but similar to indigo carmine staining endoscopy. The diagnostic accuracy rate, sensitivity and specificity of NBI were 91.5% (65/71), 81.8% (18/22) and 95.9% (47/49), which were not statistically significant when compared with indigo carmine staining endoscopy’s 88.7% (63/71), 77.3% (17/22) and 93.9% (46/49), but superior to those under conventional endoscopy. Conclusion: NBI endoscopy is superior to conventional colonoscopy in the diagnosis of colorectal hyper-plastic lesions, especially in the differentiation between neo-plastic and non-neo-plastic lesions. NBI has the advantage of showing the outlines changes of colorectal hyper-plastic lesions, PIT and CP clearly. In addition, it is easy and convenient in operation, so it is also an effective technique to make early diagnosis and has important functions in prevention of CRC.
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