TREM2 ectodomain and its soluble form in Alzheimer’s disease
Abstract Triggering receptor expressed on myeloid cells 2 (TREM2) is a receptor mainly expressed on the surface of microglia. It mediates multiple pathophysiological processes in various diseases. Recently, TREM2 has been found to play a role in the development of Alzheimer’s disease (AD). TREM2 is...
Main Authors: | Jiaolong Yang, Zhihui Fu, Xingyu Zhang, Min Xiong, Lanxia Meng, Zhentao Zhang |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2020-07-01
|
Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-020-01878-2 |
Similar Items
-
Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer’s Disease
by: Mikael Marttinen, et al.
Published: (2018-12-01) -
The Emerging Roles and Therapeutic Potential of Soluble TREM2 in Alzheimer’s Disease
by: Li Zhong, et al.
Published: (2019-11-01) -
Increased CSF Soluble TREM2 Concentration in Patients With Neurosyphilis
by: Wurong Li, et al.
Published: (2020-02-01) -
TREM2 regulates innate immunity in Alzheimer’s disease
by: Jiang-Tao Li, et al.
Published: (2018-04-01) -
The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives
by: Cody M. Wolfe, et al.
Published: (2018-12-01)