TLQP-21, A VGF-Derived Peptide Endowed of Endocrine and Extraendocrine Properties: Focus on In Vitro Calcium Signaling

TLQP-21, A VGF-Derived Peptide Endowed of Endocrine and Extraendocrine Properties: Focus on In Vitro Calcium Signaling

VGF gene encodes for a neuropeptide precursor of 68 kDa composed by 615 (human) and 617 (rat, mice) residues, expressed prevalently in the central nervous system (CNS), but also in the peripheral nervous system (PNS) and in various endocrine cells. This precursor undergoes proteolytic cleavage, gene...

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Bibliographic Details
Main Authors: Elena Bresciani, Roberta Possenti, Silvia Coco, Laura Rizzi, Ramona Meanti, Laura Molteni, Vittorio Locatelli, Antonio Torsello
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:International Journal of Molecular Sciences
Subjects:
vgf
tlqp-21
calcium (ca<sup>2+</sup>)
endocrine
extraendocrine
complement c3a receptor-1 (c3ar1)
stromal interaction molecules (stim)
calcium release-activated calcium channel (crac)-orai1
transient receptor potential channel (trpc)
kca3.1 current
Online Access:https://www.mdpi.com/1422-0067/21/1/130

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https://www.mdpi.com/1422-0067/21/1/130

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