Identification of bifurcation transitions in biological regulatory networks using Answer-Set Programming

Abstract Background Numerous cellular differentiation processes can be captured using discrete qualitative models of biological regulatory networks. These models describe the temporal evolution of the state of the network subject to different competing transitions, potentially leading the system to...

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Bibliographic Details
Main Authors: Louis Fippo Fitime, Olivier Roux, Carito Guziolowski, Loïc Paulevé
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Algorithms for Molecular Biology
Online Access:http://link.springer.com/article/10.1186/s13015-017-0110-3