Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring

Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring

A new selaginellin named selaginellin O (1), along with three other known selaginellins (2–4) were isolated from Selaginella tamariscina (Beauv.) Spring. On the basis of spectroscopic analysis, the structure of selaginellin O was demonstrated to be 4-[(4’-hydroxy-4-formyl-3-((4-hydroxyphenyl)ethynyl...

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Bibliographic Details
Main Authors: Chao Yang, Yutian Shao, Kang Li, Wujiong Xia
Format: Article
Language:English
Published: Beilstein-Institut 2012-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
antioxidant
cytotoxicity
Selaginella tamariscina
selaginellin
Online Access:https://doi.org/10.3762/bjoc.8.217
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spelling doaj-c8130d4a61944dea998fad7d3f36bdbf2021-02-02T01:38:40ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972012-11-01811884188910.3762/bjoc.8.2171860-5397-8-217Bioactive selaginellins from Selaginella tamariscina (Beauv.) SpringChao Yang0Yutian Shao1Kang Li2Wujiong Xia3State Key Lab of Urban Water Resource and Environment & the Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080, PR ChinaState Key Lab of Urban Water Resource and Environment & the Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080, PR ChinaState Key Lab of Urban Water Resource and Environment & the Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080, PR ChinaState Key Lab of Urban Water Resource and Environment & the Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080, PR ChinaA new selaginellin named selaginellin O (1), along with three other known selaginellins (2–4) were isolated from Selaginella tamariscina (Beauv.) Spring. On the basis of spectroscopic analysis, the structure of selaginellin O was demonstrated to be 4-[(4’-hydroxy-4-formyl-3-((4-hydroxyphenyl)ethynyl)biphenyl-2-yl)(4-hydroxyphenyl)methylene]cyclohexa-2,5-dien-1-one. Compound 1, 2 and 3 exhibited appreciable cytotoxic activity against cultured HeLa cells (human cervical carcinoma cells), as well as significant antioxidant activity.https://doi.org/10.3762/bjoc.8.217antioxidantcytotoxicitySelaginella tamariscinaselaginellin
collection DOAJ
language English
format Article
sources DOAJ
author Chao Yang
Yutian Shao
Kang Li
Wujiong Xia
spellingShingle Chao Yang
Yutian Shao
Kang Li
Wujiong Xia
Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring
Beilstein Journal of Organic Chemistry
antioxidant
cytotoxicity
Selaginella tamariscina
selaginellin
author_facet Chao Yang
Yutian Shao
Kang Li
Wujiong Xia
author_sort Chao Yang
title Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring
title_short Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring
title_full Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring
title_fullStr Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring
title_full_unstemmed Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring
title_sort bioactive selaginellins from selaginella tamariscina (beauv.) spring
publisher Beilstein-Institut
series Beilstein Journal of Organic Chemistry
issn 1860-5397
publishDate 2012-11-01
description A new selaginellin named selaginellin O (1), along with three other known selaginellins (2–4) were isolated from Selaginella tamariscina (Beauv.) Spring. On the basis of spectroscopic analysis, the structure of selaginellin O was demonstrated to be 4-[(4’-hydroxy-4-formyl-3-((4-hydroxyphenyl)ethynyl)biphenyl-2-yl)(4-hydroxyphenyl)methylene]cyclohexa-2,5-dien-1-one. Compound 1, 2 and 3 exhibited appreciable cytotoxic activity against cultured HeLa cells (human cervical carcinoma cells), as well as significant antioxidant activity.
topic antioxidant
cytotoxicity
Selaginella tamariscina
selaginellin
url https://doi.org/10.3762/bjoc.8.217
work_keys_str_mv AT chaoyang bioactiveselaginellinsfromselaginellatamariscinabeauvspring
AT yutianshao bioactiveselaginellinsfromselaginellatamariscinabeauvspring
AT kangli bioactiveselaginellinsfromselaginellatamariscinabeauvspring
AT wujiongxia bioactiveselaginellinsfromselaginellatamariscinabeauvspring
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