Genetically incorporated crosslinkers reveal NleE attenuates host autophagy dependent on PSMD10

Genetically incorporated crosslinkers reveal NleE attenuates host autophagy dependent on PSMD10

Autophagy acts as a pivotal innate immune response against infection. Some virulence effectors subvert the host autophagic machinery to escape the surveillance of autophagy. The mechanism by which pathogens interact with host autophagy remains mostly unclear. However, traditional strategies often ha...

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Bibliographic Details
Main Authors: Jingxiang Li, Shupan Guo, Fangni Chai, Qi Sun, Pan Li, Li Gao, Lunzhi Dai, Xiaoxiao Ouyang, Zhihui Zhou, Li Zhou, Wei Cheng, Shiqian Qi, Kefeng Lu, Haiyan Ren
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
autophagy
unnatural amino acid
covalent crosslinking
Online Access:https://elifesciences.org/articles/69047

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