A Structural Update of Neutralizing Epitopes on the HIV Envelope, a Moving Target

A Structural Update of Neutralizing Epitopes on the HIV Envelope, a Moving Target

Antibodies that can neutralize diverse HIV-1 strains develop in ~10–20% of HIV-1 infected individuals, and their elicitation is a goal of vaccine design. Such antibodies can also serve as therapeutics for those who have already been infected with the virus. Structural characterizations of broadly re...

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Bibliographic Details
Main Authors: Emma Parker Miller, Maxwell T. Finkelstein, Molly C. Erdman, Paul C. Seth, Daniela Fera
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Viruses
Subjects:
HIV-1
envelope
spike
neutralizing antibodies
epitope
neutralization
Online Access:https://www.mdpi.com/1999-4915/13/9/1774

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