Evaluation of a Methylcellulose and Hyaluronic Acid Hydrogel as a Vehicle for Rectal Delivery of Biologics

Evaluation of a Methylcellulose and Hyaluronic Acid Hydrogel as a Vehicle for Rectal Delivery of Biologics

Biologics have changed the management of Inflammatory Bowel Disease (IBD), but there are concerns regarding unexpected systemic toxicity and loss of therapeutic response following administration by injection. Local delivery of biologics directly to the inflamed mucosa via rectal enema administration...

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Bibliographic Details
Main Authors:	Andreea Aprodu, Julia Mantaj, Bahijja Raimi-Abraham, Driton Vllasaliu
Format:	Article
Language:	English
Published:	MDPI AG 2019-03-01
Series:	Pharmaceutics
Subjects:	biologics biologics delivery hyaluronic acid hydrogels inflammatory bowel disease intestinal delivery methylcellulose (MC)
Online Access:	http://www.mdpi.com/1999-4923/11/3/127

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