OXIDATIVE STRESS AND POSSIBILITY TO CORRECT IT WITH ANGIOTENSIN CONVERTING ENZYME INHIBITORS IN PATIENTS WITH MYOCARDIAL INFARCTION ASSOCIATED WITH DIABETES MELLITUS TYPE 2

The review is devoted to the modern data about mechanisms of cardiovascular dysfunction in patients suffering diabetes mellitus type 2, especially to the role of oxidative stress. It is determined that oxidative stress is involved in the development of myocardial ischemia, reperfusion-syndrome, endo...

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Main Authors: K. S. Lexina, N. Y. Timofeeva, V. S. Zadionchenko, G. G. Shehian, K. A. Aldushina
Format: Article
Language:English
Published: Stolichnaya Izdatelskaya Kompaniya 2015-12-01
Series:Racionalʹnaâ Farmakoterapiâ v Kardiologii
Subjects:
Online Access:https://www.rpcardio.com/jour/article/view/412
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spelling doaj-c7f0f2ab646d47bb8594ff5da7c7a5fb2021-09-03T13:15:15ZengStolichnaya Izdatelskaya KompaniyaRacionalʹnaâ Farmakoterapiâ v Kardiologii1819-64462225-36532015-12-0132535810.20996/1819-6446-2007-3-2-53-58412OXIDATIVE STRESS AND POSSIBILITY TO CORRECT IT WITH ANGIOTENSIN CONVERTING ENZYME INHIBITORS IN PATIENTS WITH MYOCARDIAL INFARCTION ASSOCIATED WITH DIABETES MELLITUS TYPE 2K. S. Lexina0N. Y. Timofeeva1V. S. Zadionchenko2G. G. Shehian3K. A. Aldushina4Moscow State medico-stomatological UniversityMoscow State medico-stomatological UniversityMoscow State medico-stomatological UniversityMoscow State medico-stomatological UniversityMoscow State medico-stomatological UniversityThe review is devoted to the modern data about mechanisms of cardiovascular dysfunction in patients suffering diabetes mellitus type 2, especially to the role of oxidative stress. It is determined that oxidative stress is involved in the development of myocardial ischemia, reperfusion-syndrome, endothelial dysfunction and atherogenesis. There are data that angiotensin converting enzyme inhibitor, zofenopril, has both cardio- and vasoprotective activities as well as antioxidative effect. These features are rationales to use it in patients with ischemic heart disease and diabetes mellitus.https://www.rpcardio.com/jour/article/view/412myocardial infarctiondiabetes mellitusoxidative stresszofenopril
collection DOAJ
language English
format Article
sources DOAJ
author K. S. Lexina
N. Y. Timofeeva
V. S. Zadionchenko
G. G. Shehian
K. A. Aldushina
spellingShingle K. S. Lexina
N. Y. Timofeeva
V. S. Zadionchenko
G. G. Shehian
K. A. Aldushina
OXIDATIVE STRESS AND POSSIBILITY TO CORRECT IT WITH ANGIOTENSIN CONVERTING ENZYME INHIBITORS IN PATIENTS WITH MYOCARDIAL INFARCTION ASSOCIATED WITH DIABETES MELLITUS TYPE 2
Racionalʹnaâ Farmakoterapiâ v Kardiologii
myocardial infarction
diabetes mellitus
oxidative stress
zofenopril
author_facet K. S. Lexina
N. Y. Timofeeva
V. S. Zadionchenko
G. G. Shehian
K. A. Aldushina
author_sort K. S. Lexina
title OXIDATIVE STRESS AND POSSIBILITY TO CORRECT IT WITH ANGIOTENSIN CONVERTING ENZYME INHIBITORS IN PATIENTS WITH MYOCARDIAL INFARCTION ASSOCIATED WITH DIABETES MELLITUS TYPE 2
title_short OXIDATIVE STRESS AND POSSIBILITY TO CORRECT IT WITH ANGIOTENSIN CONVERTING ENZYME INHIBITORS IN PATIENTS WITH MYOCARDIAL INFARCTION ASSOCIATED WITH DIABETES MELLITUS TYPE 2
title_full OXIDATIVE STRESS AND POSSIBILITY TO CORRECT IT WITH ANGIOTENSIN CONVERTING ENZYME INHIBITORS IN PATIENTS WITH MYOCARDIAL INFARCTION ASSOCIATED WITH DIABETES MELLITUS TYPE 2
title_fullStr OXIDATIVE STRESS AND POSSIBILITY TO CORRECT IT WITH ANGIOTENSIN CONVERTING ENZYME INHIBITORS IN PATIENTS WITH MYOCARDIAL INFARCTION ASSOCIATED WITH DIABETES MELLITUS TYPE 2
title_full_unstemmed OXIDATIVE STRESS AND POSSIBILITY TO CORRECT IT WITH ANGIOTENSIN CONVERTING ENZYME INHIBITORS IN PATIENTS WITH MYOCARDIAL INFARCTION ASSOCIATED WITH DIABETES MELLITUS TYPE 2
title_sort oxidative stress and possibility to correct it with angiotensin converting enzyme inhibitors in patients with myocardial infarction associated with diabetes mellitus type 2
publisher Stolichnaya Izdatelskaya Kompaniya
series Racionalʹnaâ Farmakoterapiâ v Kardiologii
issn 1819-6446
2225-3653
publishDate 2015-12-01
description The review is devoted to the modern data about mechanisms of cardiovascular dysfunction in patients suffering diabetes mellitus type 2, especially to the role of oxidative stress. It is determined that oxidative stress is involved in the development of myocardial ischemia, reperfusion-syndrome, endothelial dysfunction and atherogenesis. There are data that angiotensin converting enzyme inhibitor, zofenopril, has both cardio- and vasoprotective activities as well as antioxidative effect. These features are rationales to use it in patients with ischemic heart disease and diabetes mellitus.
topic myocardial infarction
diabetes mellitus
oxidative stress
zofenopril
url https://www.rpcardio.com/jour/article/view/412
work_keys_str_mv AT kslexina oxidativestressandpossibilitytocorrectitwithangiotensinconvertingenzymeinhibitorsinpatientswithmyocardialinfarctionassociatedwithdiabetesmellitustype2
AT nytimofeeva oxidativestressandpossibilitytocorrectitwithangiotensinconvertingenzymeinhibitorsinpatientswithmyocardialinfarctionassociatedwithdiabetesmellitustype2
AT vszadionchenko oxidativestressandpossibilitytocorrectitwithangiotensinconvertingenzymeinhibitorsinpatientswithmyocardialinfarctionassociatedwithdiabetesmellitustype2
AT ggshehian oxidativestressandpossibilitytocorrectitwithangiotensinconvertingenzymeinhibitorsinpatientswithmyocardialinfarctionassociatedwithdiabetesmellitustype2
AT kaaldushina oxidativestressandpossibilitytocorrectitwithangiotensinconvertingenzymeinhibitorsinpatientswithmyocardialinfarctionassociatedwithdiabetesmellitustype2
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