DNP-KLH yields weak large lymphocyte expansion and immunoglobulin isotype use with different immunization routes in zebrafish

Distinct methods are required for inducing mucosal versus systemic immunity in mammals for vaccine protection at the tissues most commonly breached by pathogens. Understanding of mucosal immunization in teleost fish is needed to combat aquaculture disease, understand emerging ecological threats, and...

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Bibliographic Details
Main Authors: Heather eWeir, Patricia L. Chen, Thaddeus C. Deiss, Natalie eJacobs, Mary B. Nabity, Matthew eYoung, Michael F. Criscitiello
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Immunology
Subjects:
IgZ
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00606/full