Female Mice Have Higher Angiogenesis in Perigonadal Adipose Tissue Than Males in Response to High-Fat Diet

Female Mice Have Higher Angiogenesis in Perigonadal Adipose Tissue Than Males in Response to High-Fat Diet

Background: Impaired capillary growth (angiogenesis) in skeletal muscle and adipose tissue contributes to the development of metabolic disorders in obese males. This association remains unexplored in females, despite mounting evidence that endothelial cells have sex-specific transcriptional profiles...

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Bibliographic Details
Main Authors: Martina Rudnicki, Ghoncheh Abdifarkosh, Omid Rezvan, Emmanuel Nwadozi, Emilie Roudier, Tara L. Haas
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Physiology
Subjects:
adipose tissue
diet-induced obesity
microvascular
sex dimorphism
skeletal muscle
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01452/full

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