<em>tert</em>-Butyl Hydroperoxide (tBHP)-Induced Lipid Peroxidation and Embryonic Defects Resemble Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in <em>C. elegans</em>

<em>tert</em>-Butyl Hydroperoxide (tBHP)-Induced Lipid Peroxidation and Embryonic Defects Resemble Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in <em>C. elegans</em>

G6PD is required for embryonic development in animals, as severe G6PD deficiency is lethal to mice, zebrafish and nematode. Lipid peroxidation is linked to membrane-associated embryonic defects in <i>Caenorhabditis elegans</i> (<i>C. elegans</i>). However, the direct link bet...

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Bibliographic Details
Main Authors: Hung-Chi Yang, Hsiang Yu, Tian-Hsiang Ma, Wen-Ye Tjong, Arnold Stern, Daniel Tsun-Yee Chiu
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
GSPD-1
tBHP
lipid peroxidation
iPLA
germ cell apoptosis
embryogenesis
Online Access:https://www.mdpi.com/1422-0067/21/22/8688

Internet

https://www.mdpi.com/1422-0067/21/22/8688

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