A review: Roles of carbohydrates in human diseases through regulation of imbalanced intestinal microbiota

• Main Authors: Xue Cheng, Junping Zheng, Aizhen Lin, Hui Xia, Zhigang Zhang, Qinghua Gao, Wenliang Lv, Hongtao Liu
• Format: Article
• Language: English
• Published: Elsevier 2020-11-01
• Series: Journal of Functional Foods
• Subjects: Carbohydrates; Gut microbiota; Prebiotics; Metabolic disease; Colorectal cancer
• Online Access: http://www.sciencedirect.com/science/article/pii/S1756464620304217

Gut microbiota plays a key role in the maintenance of human health. In most cases, carbohydrates can be fermented by gut microbiota as substrates. By such degradation reaction, the abundances, activities and metabolite production of gut microbiota will be regulated and thus prevent the occurrence of human diseases such as glycolipid metabolism disorders, enteric abnormality, aging and neurodegeneration, cancers and depression. In this paper, we reviewed the roles of carbohydrates in promoting human health through gut microbial regulation, as well as further studies on the regulatory mechanism and potential application of carbohydrates, which need to be strengthened in the future.