Mitochondria-Derived Damage-Associated Molecular Patterns in Neurodegeneration

Inflammation is increasingly implicated in neurodegenerative disease pathology. As no acquired pathogen appears to drive this inflammation, the question of what does remains. Recent advances indicate damage-associated molecular pattern (DAMP) molecules, which are released by injured and dying cells,...

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Bibliographic Details
Main Authors: Russell H. Swerdlow, Heather M. Wilkins, Ian W. Weidling, Yan Ji
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00508/full