Enteric bacteria induce IFNγ and Granzyme B from human colonic Group 1 Innate Lymphoid Cells

Enteric bacteria induce IFNγ and Granzyme B from human colonic Group 1 Innate Lymphoid Cells

Group 1 Innate Lymphoid Cells (which include Natural Killer cells and ILC1s) aid in gut anti-bacterial defense through the production of IFNγ, which is critical for mobilizing protective responses against enteric pathogens. When intestinal epithelial barrier integrity is compromised, commensal bacte...

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Bibliographic Details
Main Authors: Moriah J. Castleman, Stephanie M. Dillon, Christine Purba, Andrew C. Cogswell, Martin McCarter, Edward Barker, Cara Wilson
Format: Article
Language:English
Published: Taylor & Francis Group 2020-11-01
Series:Gut Microbes
Subjects:
group 1 ilcs
ilc1
nk cells
commensal bacteria
il-12p70
il-18
il-1β
colonic mucosa
human
ifnγ
Online Access:http://dx.doi.org/10.1080/19490976.2019.1667723

Internet

http://dx.doi.org/10.1080/19490976.2019.1667723

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