Loop diuretics in the treatment of hypertension and edema syndrome

Loop diuretics in the treatment of hypertension and edema syndrome

The comparison of the pharmacological properties, clinical efficacy of furosemide and torasemide in patients with hypertension and edema. Torasemid similar to furosemide mechanism of diuretic action but has a higher bioavailability (>80%) and a longer half-life (3-4 h). In-non-diuretic doses (2.5...

Full description

Bibliographic Details
Main Author: A A Kirichenko
Format: Article
Language:Russian
Published: IP Morozov P.V. 2016-03-01
Series:Системные гипертензии
Subjects:
arterial hypertension
torasemide
loop diuretic
Online Access:https://syst-hypertension.ru/2075-082X/article/viewFile/29132/pdf
id doaj-c7b816e820cb4c449d45ff495a02e7bb
record_format Article
spelling doaj-c7b816e820cb4c449d45ff495a02e7bb2020-11-25T03:32:55ZrusIP Morozov P.V.Системные гипертензии2075-082X2542-21892016-03-01131475126233Loop diuretics in the treatment of hypertension and edema syndromeA A Kirichenko0Russian Medical Academy of Postgraduate Education of the Ministry of Health of the Russian FederationThe comparison of the pharmacological properties, clinical efficacy of furosemide and torasemide in patients with hypertension and edema. Torasemid similar to furosemide mechanism of diuretic action but has a higher bioavailability (>80%) and a longer half-life (3-4 h). In-non-diuretic doses (2.5-5 mg/day) torasemide used in the treatment of essential hypertension, both as monotherapy and in combination with other antihypertensive drugs. When used in these doses torasemide reduces diastolic blood pressure to below 90 mm Hg in 70-80% of patients. In patients with chronic heart failure torasemide in a dose of from 5 to 20 mg/day is an effective diuretic. The bioavailability of torasemide when administered in patients with CHF decreases only slightly, the diuretic action is smoother, it is less likely to cause the phenomenon of "rebound". Total and cardiovascular mortality in patients treated with torasemide, was lower (2.2% compared with 4.5% in the comparison group; phttps://syst-hypertension.ru/2075-082X/article/viewFile/29132/pdfarterial hypertensiontorasemideloop diuretic
collection DOAJ
language Russian
format Article
sources DOAJ
author A A Kirichenko
spellingShingle A A Kirichenko
Loop diuretics in the treatment of hypertension and edema syndrome
Системные гипертензии
arterial hypertension
torasemide
loop diuretic
author_facet A A Kirichenko
author_sort A A Kirichenko
title Loop diuretics in the treatment of hypertension and edema syndrome
title_short Loop diuretics in the treatment of hypertension and edema syndrome
title_full Loop diuretics in the treatment of hypertension and edema syndrome
title_fullStr Loop diuretics in the treatment of hypertension and edema syndrome
title_full_unstemmed Loop diuretics in the treatment of hypertension and edema syndrome
title_sort loop diuretics in the treatment of hypertension and edema syndrome
publisher IP Morozov P.V.
series Системные гипертензии
issn 2075-082X
2542-2189
publishDate 2016-03-01
description The comparison of the pharmacological properties, clinical efficacy of furosemide and torasemide in patients with hypertension and edema. Torasemid similar to furosemide mechanism of diuretic action but has a higher bioavailability (>80%) and a longer half-life (3-4 h). In-non-diuretic doses (2.5-5 mg/day) torasemide used in the treatment of essential hypertension, both as monotherapy and in combination with other antihypertensive drugs. When used in these doses torasemide reduces diastolic blood pressure to below 90 mm Hg in 70-80% of patients. In patients with chronic heart failure torasemide in a dose of from 5 to 20 mg/day is an effective diuretic. The bioavailability of torasemide when administered in patients with CHF decreases only slightly, the diuretic action is smoother, it is less likely to cause the phenomenon of "rebound". Total and cardiovascular mortality in patients treated with torasemide, was lower (2.2% compared with 4.5% in the comparison group; p
topic arterial hypertension
torasemide
loop diuretic
url https://syst-hypertension.ru/2075-082X/article/viewFile/29132/pdf
work_keys_str_mv AT aakirichenko loopdiureticsinthetreatmentofhypertensionandedemasyndrome
_version_ 1724565961822961664

Similar Items