A new dynamic correlation algorithm reveals novel functional aspects in single cell and bulk RNA-seq data.

Dynamic correlations are pervasive in high-throughput data. Large numbers of gene pairs can change their correlation patterns in response to observed/unobserved changes in physiological states. Finding changes in correlation patterns can reveal important regulatory mechanisms. Currently there is no...

Full description

Bibliographic Details
Main Author: Tianwei Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC6095616?pdf=render