A Marine Collagen-Based Biomimetic Hydrogel Recapitulates Cancer Stem Cell Niche and Enhances Progression and Chemoresistance in Human Ovarian Cancer

A Marine Collagen-Based Biomimetic Hydrogel Recapitulates Cancer Stem Cell Niche and Enhances Progression and Chemoresistance in Human Ovarian Cancer

Recent attention has focused on the development of an effective three-dimensional (3D) cell culture system enabling the rapid enrichment of cancer stem cells (CSCs) that are resistant to therapies and serving as a useful in vitro tumor model that accurately reflects in vivo behaviors of cancer cells...

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Bibliographic Details
Main Authors: SooHyeon Moon, YeJin Ok, SeonYeong Hwang, Ye Seon Lim, Hye-Yoon Kim, Yong-Jin Na, Sik Yoon
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Marine Drugs
Subjects:
marine collagen
hydrogel
cancer stem cell
ovarian cancer
3D cell culture
spheroid
Online Access:https://www.mdpi.com/1660-3397/18/10/498

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