The Non-Essential Amino Acid Cysteine Becomes Essential for Tumor Proliferation and Survival
The non-essential amino acid cysteine is used within cells for multiple processes that rely on the chemistry of its thiol group. Under physiological conditions, many non-transformed tissues rely on glutathione, circulating cysteine, and the de novo cysteine synthesis (transsulfuration) pathway as so...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-05-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/11/5/678 |