Failure of Warfarin Anticoagulation Therapy after Administration of Oral Terbinafine
Warfarin is widely used anticoagulant drug for a variety of diseases (thromboembolic disease, atrial fibrillation, etc.). It has three most important parallel metabolic pathways, CYP1A2, CYP3A4 and CYP2C9. Terbinafine is a potent CYP2D6 inhibitor. A possible drug interaction could lead to an increas...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Karolinum Press
2021-08-01
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| Series: | Acta Medica |
| Online Access: | https://actamedica.lfhk.cuni.cz/64/2/0132/ |