Immune-mediated bone marrow failure syndromes of progenitor and stem cells: molecular analysis of cytotoxic T cell clones.

The unique structure of the T cell receptor (TCR) enables molecular identification of individual T cell clones and provides an unique opportunity for the design of molecular diagnostic tests based on the structure of the rearranged TCR chain e.g., using the TCR CDR3 region. Initially, clonal T cell...

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Bibliographic Details
Main Authors: Ramon Tiu, Lukasz Gondek, Christine O' Keefe, Jaroslaw P Maciejewski
Format: Article
Language:English
Published: Via Medica 2007-03-01
Series:Folia Histochemica et Cytobiologica
Online Access:http://czasopisma.viamedica.pl/fhc/article/view/4544

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