Anterior hypopituitarism secondary to biopsy-proven IgG4-related hypophysitis in a young man

Anterior hypopituitarism secondary to biopsy-proven IgG4-related hypophysitis in a young man

IgG4-related disease (IgG4-RD) is an immune-mediated fibro-inflammatory condition which can affect various organs including the pituitary gland. The true annual incidence of this condition remains widely unknown. In addition, it is unclear whether IgG4 antibodies are causative or the end result of a...

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Main Authors: H Joshi, M Hikmat, A P Devadass, S O Oyibo, S V Sagi
Format: Article
Language:English
Published: Bioscientifica 2019-04-01
Series:Endocrinology, Diabetes & Metabolism Case Reports
Online Access:https://edm.bioscientifica.com/view/journals/edm/2019/1/EDM18-0137.xml
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spelling doaj-c79ba62624674a6190e5c7534facd5ba2020-11-25T00:45:03ZengBioscientificaEndocrinology, Diabetes & Metabolism Case Reports2052-05732052-05732019-04-01111510.1530/EDM-18-0137Anterior hypopituitarism secondary to biopsy-proven IgG4-related hypophysitis in a young manH Joshi0M Hikmat1A P Devadass2S O Oyibo3S V Sagi4Department of Endocrinology, Peterborough City Hospital, Peterborough, UKDepartment of Endocrinology, Peterborough City Hospital, Peterborough, UKDepartment of Histopathology, Addenbrookes Hospital, Cambridge, UKDepartment of Endocrinology, Peterborough City Hospital, Peterborough, UKDepartment of Endocrinology, Peterborough City Hospital, Peterborough, UKIgG4-related disease (IgG4-RD) is an immune-mediated fibro-inflammatory condition which can affect various organs including the pituitary gland. The true annual incidence of this condition remains widely unknown. In addition, it is unclear whether IgG4 antibodies are causative or the end result of a trigger. With no specific biomarkers available, the diagnosis of IgG4-related hypophysitis remains a challenge. Additionally, there is a wide differential diagnosis. We report a case of biopsy-proven IgG4-related hypophysitis in a young man with type 2 diabetes mellitus.https://edm.bioscientifica.com/view/journals/edm/2019/1/EDM18-0137.xml
collection DOAJ
language English
format Article
sources DOAJ
author H Joshi
M Hikmat
A P Devadass
S O Oyibo
S V Sagi
spellingShingle H Joshi
M Hikmat
A P Devadass
S O Oyibo
S V Sagi
Anterior hypopituitarism secondary to biopsy-proven IgG4-related hypophysitis in a young man
Endocrinology, Diabetes & Metabolism Case Reports
author_facet H Joshi
M Hikmat
A P Devadass
S O Oyibo
S V Sagi
author_sort H Joshi
title Anterior hypopituitarism secondary to biopsy-proven IgG4-related hypophysitis in a young man
title_short Anterior hypopituitarism secondary to biopsy-proven IgG4-related hypophysitis in a young man
title_full Anterior hypopituitarism secondary to biopsy-proven IgG4-related hypophysitis in a young man
title_fullStr Anterior hypopituitarism secondary to biopsy-proven IgG4-related hypophysitis in a young man
title_full_unstemmed Anterior hypopituitarism secondary to biopsy-proven IgG4-related hypophysitis in a young man
title_sort anterior hypopituitarism secondary to biopsy-proven igg4-related hypophysitis in a young man
publisher Bioscientifica
series Endocrinology, Diabetes & Metabolism Case Reports
issn 2052-0573
2052-0573
publishDate 2019-04-01
description IgG4-related disease (IgG4-RD) is an immune-mediated fibro-inflammatory condition which can affect various organs including the pituitary gland. The true annual incidence of this condition remains widely unknown. In addition, it is unclear whether IgG4 antibodies are causative or the end result of a trigger. With no specific biomarkers available, the diagnosis of IgG4-related hypophysitis remains a challenge. Additionally, there is a wide differential diagnosis. We report a case of biopsy-proven IgG4-related hypophysitis in a young man with type 2 diabetes mellitus.
url https://edm.bioscientifica.com/view/journals/edm/2019/1/EDM18-0137.xml
work_keys_str_mv AT hjoshi anteriorhypopituitarismsecondarytobiopsyprovenigg4relatedhypophysitisinayoungman
AT mhikmat anteriorhypopituitarismsecondarytobiopsyprovenigg4relatedhypophysitisinayoungman
AT apdevadass anteriorhypopituitarismsecondarytobiopsyprovenigg4relatedhypophysitisinayoungman
AT sooyibo anteriorhypopituitarismsecondarytobiopsyprovenigg4relatedhypophysitisinayoungman
AT svsagi anteriorhypopituitarismsecondarytobiopsyprovenigg4relatedhypophysitisinayoungman
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