Identification of the protease cleavage sites in a reconstituted Gag polyprotein of an HERV-K(HML-2) element

Identification of the protease cleavage sites in a reconstituted Gag polyprotein of an HERV-K(HML-2) element

<p>Abstract</p> <p>Background</p> <p>The human genome harbors several largely preserved HERV-K(HML-2) elements. Although this retroviral family comes closest of all known HERVs to producing replication competent virions, mutations acquired during their chromosomal resid...

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Bibliographic Details
Main Authors: Kurth Reinhard, Zimmermann Anja, Chudak Claudia, Hohn Oliver, Beimforde Nadine, Schwecke Torsten, George Maja, Naumann Dieter, Bannert Norbert
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Retrovirology
Subjects:
HERV-K(HML-2)
Gag processing
maturation
retrovirus
retroviral protease
endogenous retrovirus
Online Access:http://www.retrovirology.com/content/8/1/30

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