CROSS-REACTIVITY OF TCR REPERTOIRE: CURRENT CONCEPTS, CHALLENGES AND IMPLICATION FOR ALLOTRANSPLANTATION

Being able to track donor reactive T cells during the course of organ transplantation is key to improve the graft survival, to prevent graft dysfunction and to adapt the immunosuppressive regimen. The attempts of transplant immunologists have been for long hampered by the large size of the alloreact...

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Bibliographic Details
Main Authors: Nicolas eDegauque, Sophie eBrouard, Jean-Paul eSoulillou
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Immunology
Subjects:
tcr
MHC
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00089/full