Why humans and Catarrhini lack the Galα1-3Gal epitope, related to xenograft rejection?
The Galα1-3Gal epitope (Galβ1-3Galα1-4GlcNAc-R) is an oligosaccharide determinant present on the cell surface of most mammalian species with the exception of the higher primates, including Old World monkeys, apes, and humans. The synthesis of Galα1-3Gal epitope is catalyzed by α1,3-galactosyltransfe...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Index Copernicus International S.A.
2009-06-01
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Series: | Postępy Higieny i Medycyny Doświadczalnej |
Subjects: | |
Online Access: | http://journals.indexcopernicus.com/fulltxt.php?ICID=887414 |