Why humans and Catarrhini lack the Galα1-3Gal epitope, related to xenograft rejection?

The Galα1-3Gal epitope (Galβ1-3Galα1-4GlcNAc-R) is an oligosaccharide determinant present on the cell surface of most mammalian species with the exception of the higher primates, including Old World monkeys, apes, and humans. The synthesis of Galα1-3Gal epitope is catalyzed by α1,3-galactosyltransfe...

Full description

Bibliographic Details
Main Authors: Anna Suchanowska, Marcin Czerwiński
Format: Article
Language:English
Published: Index Copernicus International S.A. 2009-06-01
Series:Postępy Higieny i Medycyny Doświadczalnej
Subjects:
α1
Online Access:http://journals.indexcopernicus.com/fulltxt.php?ICID=887414