Data on genetic linkage of oxidative stress with cardiometabolic traits in an intercross derived from hyperlipidemic mouse strains

The data presented here are related to the research article, entitled Genetic linkage of oxidative stress with cardiometabolic traits in an intercross derived from hyperlipidemic mouse strains, published in Atherosclerosis 2019 Dec 3;293:1–10 (D. Fuller, A.T. Grainger, A. Manichaikul, W. Shi). The s...

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Bibliographic Details
Main Authors: Daniela T. Fuller, Andrew T. Grainger, Ani Manichaikul, Weibin Shi
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340920300597
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Summary:The data presented here are related to the research article, entitled Genetic linkage of oxidative stress with cardiometabolic traits in an intercross derived from hyperlipidemic mouse strains, published in Atherosclerosis 2019 Dec 3;293:1–10 (D. Fuller, A.T. Grainger, A. Manichaikul, W. Shi). The supporting materials include original genotypic and phenotypic data obtained from 266 female F2 mice derived from an intercross between C57BL/6 (B6) and BALB/cJ (BALB) Apoe−/- mice. F2 mice were fed 12 weeks of Western diet, starting at 6 weeks of age. Plasma levels of HDL, LDL cholesterol, triglycerides, glucose and malondialdehyde (MDA) and atherosclerosis in the aortic root and the left carotid artery were measured. 127 microsatellite markers across the entire genome were genotyped. The data is provided in the format ready for QTL analysis with J/qtl and MapManager QTX. Keywords: Genetic linkage, Oxidative stress, Cardiometabolic trait, Atherosclerosis, Mouse
ISSN:2352-3409