PLZF controls the expression of a limited number of genes essential for NKT cell function

PLZF controls the expression of a limited number of genes essential for NKT cell function

Natural killer (NKT) T cells exhibit tissue distribution, surface phenotype, and functional responses that are strikingly different from those of conventional T cells. The transcription factor PLZF is responsible for most of these properties, as its ectopic expression in conventional T cells is suff...

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Bibliographic Details
Main Authors: Michael eGleimer, Harald eVon Boehmer, Taras eKreslavsky
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-12-01
Series:Frontiers in Immunology
Subjects:
PLZF
NKT
c-Maf
Id2
CXCR6
ICOS
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00374/full

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