Role of Collagen Fiber Morphology on Ovarian Cancer Cell Migration Using Image-Based Models of the Extracellular Matrix

Role of Collagen Fiber Morphology on Ovarian Cancer Cell Migration Using Image-Based Models of the Extracellular Matrix

Remodeling of the extracellular matrix (ECM) is an important part in the development and progression of many epithelial cancers. However, the biological significance of collagen alterations in ovarian cancer has not been well established. Here we investigated the role of collagen fiber morphology on...

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Bibliographic Details
Main Authors: Samuel Alkmin, Rebecca Brodziski, Haleigh Simon, Daniel Hinton, Randall H. Goldsmith, Manish Patankar, Paul J. Campagnola
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
collagen
ovarian stroma
motility
Second-Harmonic Generation
multiphoton excited
cytoskeleton
Online Access:https://www.mdpi.com/2072-6694/12/6/1390

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