Comparative analysis of the chicken IFITM locus by targeted genome sequencing reveals evolution of the locus and positive selection in IFITM1 and IFITM3

Comparative analysis of the chicken IFITM locus by targeted genome sequencing reveals evolution of the locus and positive selection in IFITM1 and IFITM3

Abstract Background The interferon-induced transmembrane (IFITM) protein family comprises a class of restriction factors widely characterised in humans for their potent antiviral activity. Their biological activity is well documented in several animal species, but their genetic variation and biologi...

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Bibliographic Details
Main Authors: Irene Bassano, Swee Hoe Ong, Maximo Sanz-Hernandez, Michal Vinkler, Adebabay Kebede, Olivier Hanotte, Ebele Onuigbo, Mark Fife, Paul Kellam
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Genomics
Subjects:
Variant calling
SNPs
INDELs
GATK
Positive selection
Online Access:http://link.springer.com/article/10.1186/s12864-019-5621-5

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