Improvement of Physico-mechanical Properties of Partially Amorphous Acetaminophen Developed from Hydroalcoholic Solution Using Spray Drying Technique

Improvement of Physico-mechanical Properties of Partially Amorphous Acetaminophen Developed from Hydroalcoholic Solution Using Spray Drying Technique

  Objective(s): This study was performed aiming to investigate the effect of particle engineering via spray drying of hydroalcoholic solution on solid states and physico-mechanical properties of acetaminophen.   Materials and Methods: Spray drying of hydroalcoholic solution (25% v/v ethanol/water) o...

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Bibliographic Details
Main Authors: Fatemeh Sadeghi, Mansour Torab, Mostafa Khattab, Alireza Homayouni, Hadi Afrasiabi Garekani
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2013-10-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Acetaminophen Amorphous particles Compaction Crystallinity Dissolution Spray drying
Online Access:http://ijbms.mums.ac.ir/pdf_1873_19d415a3152db87253f8a8b65867a268.html

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