Candida glabrata as an aetiological factor of the fulminant course of panophthalmitis

• Main Authors: Joanna Bilska-Stokłosa, Katarzyna Hampelska, Krzysztof Osmola, Jędrzej Czajka, Dorota Bogdanowicz-Gapińska, Hanna Tomczak
• Format: Article
• Language: English
• Published: Institute of Rural Health 2020-12-01
• Series: Annals of Agricultural and Environmental Medicine
• Subjects: panophthalmitis; candida glabrata; corneal transplant
• Online Access: http://www.aaem.pl/-Candida-glabrata-as-an-aetiological-factor-of-the-fulminant-course-of-panophthalmitis,122475,0,2.html

Introduction The role of fungi in infections in immunocompromised patients is a growing problem in both diagnosis and treatment. Candida species are the most common cause of fungal, endogenous endophthalmitis and infections of the cornea. Case study A patient was admitted to hospital due to acute inflammation of the tissue of the left orbit, 1.5 years after the corneal penetrating transplantation of the left eye with intracapsular extraction of lens and simultaneous anterior vitrectomy. The microbiological system identified: Streptococcus pyogenes, Staphylococcus aureus, and Candida glabrata in the patient. Conclusions The factors conducive to fungal infections are: patient’s old age, immune disorders and diabetes, as well as the presence of a necrotic tissue or a foreign body. All these parameters were met in this case. Only antibiotic therapy and long-term antifungal therapy, together with surgical debridement of the site of the ongoing infection produces clinical effects in such severe cases.