Use of Oral Miltefosine for Cutaneous Leishmaniasis in Canadian Soldiers Returning from Afghanistan

Use of Oral Miltefosine for Cutaneous Leishmaniasis in Canadian Soldiers Returning from Afghanistan

Old world cutaneous leishmaniasis (CL) is caused by Leishmania major and Leishmania tropica, and is endemic to several Asian and Middle-Eastern countries where the rates of infection can be substantial. CL is one of the most common vector-transmitted parasitic infections in Afghanistan. Six cases of...

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Main Authors: Yoav Keynan, Oscar E Larios, Marni C Wiseman, Marie Plourde, Marc Ouellette, Ethan Rubinstein
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2008/802710
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spelling doaj-c74628eaf0c443d2a24c60436e7f29de2021-07-02T03:27:12ZengHindawi LimitedCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322008-01-0119639439610.1155/2008/802710Use of Oral Miltefosine for Cutaneous Leishmaniasis in Canadian Soldiers Returning from AfghanistanYoav Keynan0Oscar E Larios1Marni C Wiseman2Marie Plourde3Marc Ouellette4Ethan Rubinstein5Departments of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, CanadaDepartments of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, CanadaSection of Dermatology, Department of Medicine, University of Manitoba, Winnipeg, Manitoba, CanadaCentre de Recherche en Infectiologie du Centre de Recherche du CHUL, Département de Microbiologie, Faculté de Médecine, Université Laval, Laval, Quebec, CanadaCentre de Recherche en Infectiologie du Centre de Recherche du CHUL, Département de Microbiologie, Faculté de Médecine, Université Laval, Laval, Quebec, CanadaDepartments of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, CanadaOld world cutaneous leishmaniasis (CL) is caused by Leishmania major and Leishmania tropica, and is endemic to several Asian and Middle-Eastern countries where the rates of infection can be substantial. CL is one of the most common vector-transmitted parasitic infections in Afghanistan. Six cases of CL in Canadian soldiers returning from Afghanistan are reported in the present study. Their lesions did not improve with fluconazole therapy, and the organism demonstrated in vitro resistance. Oral miltefosine seemed effective.http://dx.doi.org/10.1155/2008/802710
collection DOAJ
language English
format Article
sources DOAJ
author Yoav Keynan
Oscar E Larios
Marni C Wiseman
Marie Plourde
Marc Ouellette
Ethan Rubinstein
spellingShingle Yoav Keynan
Oscar E Larios
Marni C Wiseman
Marie Plourde
Marc Ouellette
Ethan Rubinstein
Use of Oral Miltefosine for Cutaneous Leishmaniasis in Canadian Soldiers Returning from Afghanistan
Canadian Journal of Infectious Diseases and Medical Microbiology
author_facet Yoav Keynan
Oscar E Larios
Marni C Wiseman
Marie Plourde
Marc Ouellette
Ethan Rubinstein
author_sort Yoav Keynan
title Use of Oral Miltefosine for Cutaneous Leishmaniasis in Canadian Soldiers Returning from Afghanistan
title_short Use of Oral Miltefosine for Cutaneous Leishmaniasis in Canadian Soldiers Returning from Afghanistan
title_full Use of Oral Miltefosine for Cutaneous Leishmaniasis in Canadian Soldiers Returning from Afghanistan
title_fullStr Use of Oral Miltefosine for Cutaneous Leishmaniasis in Canadian Soldiers Returning from Afghanistan
title_full_unstemmed Use of Oral Miltefosine for Cutaneous Leishmaniasis in Canadian Soldiers Returning from Afghanistan
title_sort use of oral miltefosine for cutaneous leishmaniasis in canadian soldiers returning from afghanistan
publisher Hindawi Limited
series Canadian Journal of Infectious Diseases and Medical Microbiology
issn 1712-9532
publishDate 2008-01-01
description Old world cutaneous leishmaniasis (CL) is caused by Leishmania major and Leishmania tropica, and is endemic to several Asian and Middle-Eastern countries where the rates of infection can be substantial. CL is one of the most common vector-transmitted parasitic infections in Afghanistan. Six cases of CL in Canadian soldiers returning from Afghanistan are reported in the present study. Their lesions did not improve with fluconazole therapy, and the organism demonstrated in vitro resistance. Oral miltefosine seemed effective.
url http://dx.doi.org/10.1155/2008/802710
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AT marnicwiseman useoforalmiltefosineforcutaneousleishmaniasisincanadiansoldiersreturningfromafghanistan
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AT marcouellette useoforalmiltefosineforcutaneousleishmaniasisincanadiansoldiersreturningfromafghanistan
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