PM00104 (Zalypsis®): A Marine Derived Alkylating Agent

PM00104 (Zalypsis®) is a synthethic tetrahydroisoquinolone alkaloid, which is structurally similar to many marine organisms. The compound has been proposed as a potential chemotherapeutic agent in the treatment of solid human tumors and hematological malignancies. PM00104 is a DNA binding agent, c...

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Bibliographic Details
Main Authors: Bradley J. Petek, Robin L. Jones
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/8/12328