PARP-14 Promotes Survival of Mammalian α but Not β Pancreatic Cells Following Cytokine Treatment

PARP-14 Promotes Survival of Mammalian α but Not β Pancreatic Cells Following Cytokine Treatment

PARP-14 (poly-ADP Ribose Polymerase-14), a member of the PARP family, belongs to the group of Bal proteins (B Aggressive Lymphoma). PARP-14 has recently appeared to be involved in the transduction pathway mediated by JNKs (c Jun N terminal Kinases), among which JNK2 promotes cancer cell survival. Se...

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Bibliographic Details
Main Authors: Floriana D'Angeli, Marina Scalia, Matilde Cirnigliaro, Cristina Satriano, Vincenza Barresi, Nicolò Musso, Angela Trovato-Salinaro, Davide Barbagallo, Marco Ragusa, Cinzia Di Pietro, Michele Purrello, Vittoria Spina-Purrello
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Endocrinology
Subjects:
PARP-14
JNK1
JNK2
cytokines
PJ-34
survival
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00271/full

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