Connections between EM2-containing terminals and GABA/µ-opioid receptor co-expressing neurons in the rat spinal trigeminal caudal nucleus

Connections between EM2-containing terminals and GABA/µ-opioid receptor co-expressing neurons in the rat spinal trigeminal caudal nucleus

Endomorphin-2 (EM2) demonstrates a potent antinociceptive effect via the µ-opioid receptor (MOR). To provide morphological evidence for the pain control effect of EM2, the synaptic connections between EM2-immunoreactive (IR) axonal terminals and γ-amino butyric acid (GABA)/ MOR co-expressing neurons...

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Bibliographic Details
Main Authors: Meng-Ying eLi, Zheng-Yu eWu, Ya-Cheng eLu, Jun-Bin eYin, Jian eWang, Ting eZhang, Yu-Lin eDong, Feng eWang
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Neural Circuits
Subjects:
synapse
inhibitory interneuron
endomorphin 2
γ-amino butyric acid
µ opioid receptor
spinal trigeminal caudal nucleus
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2014.00125/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncir.2014.00125/full

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