Effect of Autophagy Regulated by Sirt1/FoxO1 Pathway on the Release of Factors Promoting Thrombosis from Vascular Endothelial Cells

Factors promoting thrombosis such as von Willebrand factor (vWF) and P-selectin are essential for the development of atherosclerosis (AS) and arterial thrombosis. The processing, maturation and release of vWF are regulated by autophagy of vascular endothelial cells. The Sirt1/FoxO1 pathway is an imp...

Full description

Bibliographic Details
Main Authors: Qian Wu, Yuting Hu, Minrui Jiang, Fanglei Wang, Guoqing Gong
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
vWF
Online Access:https://www.mdpi.com/1422-0067/20/17/4132